Leanardo da Vinci invented some kick-ass military weapons. He also might have been gay.
Here's that painting they found that could be the R-rated version of the Mona Lisa. Should I have marked this post NSFW? Oh well, deal with it.
I'll bet that if da Vinci did paint his face on a woman's body, his contemporaries would have thought it was just a goof, like when Milton Berle wore a dress on TV in the fifties. They would crack up if they saw it being treated as serious art.